The Sophisticated Analytical Instrument Facility (SAIF), formerly known as Regional Sophisticated Instrumentation Centre (RSIC) at North-Eastern Hill University (NEHU), Shillong was established on 7^thJuly, 1984 by the Department of Science and Technology (DST), Government of India, New Delhi. Initially analytical services of SAIF Shillong offered were based on equipment pooled in by NEHU and subsequently a wide range of new sophisticated analytical instruments funded by DST were added based on the scientists' requisition to pursue R & D activities. Currently, the Centre provides a comprehensive suite of analytical instrumentation services, which includes TEM, SEM, Microscope with image analyzer, FT-NMR, ICP-OES, GF-AAS and LC-MS.