Dr. R. L Nongkhlaw

Chemistry Department

Designation: Associate Professor

Qualifications:

M.Sc (NEHU), Ph.D (NEHU)

Areas of Interest/Specialization: 

Organic Chemistry

Research Interest:

  • Synthesis of pharmacologically important Heterocycles:    Synthetic approaches to Oxygen, Nitrogen and Sulphur Heterocycles via green protocols and studies on their biological properties.
    Synthesis of Nanoparticles and organo-nanocatalysts:   Preparation of metal (ferromagnetic as well as non-ferromagnetic) nanoparticles via chemical methods, and investigation on its catalytic properties in organic synthesis. Development of coated/ hybrid organo-nanocatalyst for advanced synthesis

Experience: 16 Years 

PhD Awarded/Supervised: 

Awarded: 8

  • Dr. Jims World Star Rani
  • Dr. Geetmani Singh Nongthombam
  • Dr. Chingrishon Kathing
  • Dr. Shokip Tumtin
  • Dr. Satyapati Devi
  • Dr. Tovishe Phucho
  • Dr. Madhushudhan Saha
  • Dr. Milan Chandra Dutta

Result Awaited: 2

  • Mrs Ridaphun Nongrum
  • Mr. Noimur Rahman

Ongoing: 5

  • Mr George Kupar Kharmawlong
  • Mr Aiborlang Thongni
  • Mr Arup Dutta
  • Ms Munmee Medhi
  • Ms Pooja Paul

        MSc. Project Students Supervised: 30

Administrative responsibilities undertaken:

  • Warden, Ranggira Hostel, Hostel No 19: From August 2008 till September 2015.
  • University Proctor (Shillong Campus), NEHU:  2015-Onwards.
  • Convener of the Anti-Ragging Committee.
  • Convener of the Anti-Ragging Squad.
  • Member of Election Commission of NEHUSU.
  • Member of the University Level Disciplinary Council.
  • Member of the Residential Allotment Committee for Hostel allotment.
  • Member of the Students Counselling Cell.
  • Member of the Committee for University Memorabilia.
  • Chairman of “The Chemistry Club, Department of Chemistry” from 2012 onwards.
  • Nodal Officer for the Awareness programmes on Drug abuse and prevention in Colleges and central Universities.

Academic affiliations :

  • Life member of The Indian Science Congress Association, Kolkata
  • Life member of the Indian Council of Chemists
  • Life member of The Chemical Research Society of India
  • Member, Board of Under Graduate Studies in Chemistry, NEHU
  • Member, Board of Post Graduate Studies in Chemistry, NEHU
  • Member, Board of Post Graduate Studies in Biochemistry, NEHU
  • Member, School Board of Physical Sciences, NEHU
  • Member, Board of Studies in Chemistry, NEHU
  • Member, Admission Committee for PhD and MSc.
  • Member, Meghalaya Medical Entrance Test (MMET)

Research Projects

  • (On going) Department of Science and Technology (DST) sponsored project entitled “Synthetic studies on organo encapsulated nanoparticles for fabrication of C-N, C-O, C-S bonds leading to 5- and 6-membered rings.”

Publications

  • R. Nongrum, G. Kharmawlong, J. W. S. Rani, N. Rahman, A. Dutta and R. Nongkhlaw; Organocatalytic Green Approach Towards the Fabrication of Fused Benzo N,?N-?containing Heterocycles Facilitated by Ultrasonic Irradiation. Journal of Heterocyclic Chemistry, 2019, DOI:10.1002/jhet.3680.
  • G. K. Kharmawlong, R. Nongrum, B. Chhetri, J.W. S. Rani, N. Rahman; A. K. Yadav and R Nongkhlaw; Green and efficient one-?pot synthesis of 2,?3-?dihydroquinazolin-?4(1H)?-?ones and their anthelmintic studies, Synthetic Communications2019, 49(20), 2683-2695. doi.org/10.1080/00397911.2019.1639754.
  • R. Nongrum, G. S. Nongthombam, J. W. S. Rani, N. Rahman, G. Kharmawlong and R. Nongkhlaw; [1,?3]?oxazines: green synthesis by sonication using a magnetically-?separable basic nano-?catalyst and investigation of its biological activity, Environmental Chemistry Letters, 2019, 17(3), 1325-1331.
  •  R. Nongkhlaw, R. Nongrum, S. Tumtin, and I. T. Phucho; Green and efficient synthesis of 1,?2-?bis(2H-?benzo[e]?[1,?3]?oxazin-?3(4H)?-?yl)?ethanes and 1,?2-?bis(2H-?benzo[e]?[1,?3]?thiazin-?3(4H)?-?yl)?ethanes;   ARKIVOC, 2019, (5), 255-264. DOI:10.24820/ark.5550190.p010.854.
  • N. Rahman, G. S. Nongthombam, J. W. S. Rani, R. Nongrum and R.Nongkhlaw, An environment friendly magnetic organo-nanomaterial as a potent catalyst in synthesis of pyranopyrazole derivatives, Arkivoc, 2019, part v, 255-264, DOI: https://doi.org/10.24820/ark.5550190.p010.720.
  •  
  • N. Rahman, G. S. Nongthombam, J. W. S. Rani, R. Nongrum, G. K. Kharmawlong and R. Nongkhlaw; An environment-friendly magnetic organo-nanomaterial as a potent catalyst in synthesis of pyranopyrazole derivatives. Current Organocatalysis, 2018, 5(2), 150 – 161.
  • N. G. Singh, G. K. Kharmawlong, J. E. Kumar and R. Nongkhlaw; UV-365 light promoted catalyst-free synthesis of pyrimido[4,5-b] quinoline-2,4-diones in aqueous-glycerol medium. New Journal of Chemistry, 2018, 42, 9436- 9442.
  • N. G. Singh and R. Nongkhlaw; Experimental and theoretical studies on SPION@glutathione catalyzed synthesis of indolyl chromene, indolo xanthene and pyrimido[4,5 b]quinoline. Synthetic Communications, , 2018, 48(5), 541- 552.
  • R. Nongrum, G. S. Nongthombam, M. Kharkongor, J. W. S. Rani, N.  Rahman, C. Kathing, B. Myrboh and R. Nongkhlaw; A Nano-organo catalyzed route towards the efficient synthesis of benzo[b]pyran derivatives under Ultrasonic irradiation. RSC Adv., 2016,6, 108384-108392.
  • J.W.S. Rani, C. Kathing, N. G. Singh, R. Nongrum, N. Rahman, G. Kharmawlong, R. Nongkhlaw; One-pot synthesis of 3, 4-dihydropyrimidin-2(1H)-ones catalysed by [BMIM]Br under solvent-free condition. Bulgarian Chemical Communications, 2016, 48(4), 3–10.
  • C. Kathing, S. Kumar, S. Tumtin, N. G. Singh, Jims W. S. Rani, R. Nongrum, and R. Nongkhlaw; N,N′-Dialkyl-4-Aryl-3,4-Dihydropyrimidinones and Thiones: Ceric Ammonium Nitrate Catalyzed Synthesis and Molecular Structure Determination by X-ray Crystallography. Journal of Heterocyclic Chemistry, 2016, 54(2), 2735- 2738.
  • N. G. Singh, M. Lily, S. P. Devi, N. Rahman, A. Ahmed, A. K. Chandra and R. Nongkhlaw; Synthetic, mechanistic and kinetic studies on the organo-nanocatalyzed synthesis of oxygen and nitrogen containing spiro compounds under ultrasonic conditions.  Green Chem., 2016, 18, 4216-4227.
  • N. G. Singh, R. Nagarajaprakash, J. W. S. Rani, C. Kathing, R. Nongrum and R. Nongkhlaw; Nickel nanoparticles assisted regioselective synthesis of pyrazoloquinolinone and triazolo-quinazolinone derivatives. New J. Chem., 2015, 39, 3908-3915.
  • S. Tumtin, C. Kathing, I. T, Phucho, R. Nongrum, B. Myrboh and R. Nongkhlaw; Triethylbenzylammonium chloride as a useful and efficient catalyst for the alkylation of Indole/substituted Indoles in Water: A Comparative Study between Conventional and Microwave Irradiation. J. Chin. Chem. Soc., 2015, 62(4), 321–327.
  • C. Kathing, Jims W. S. Rani, Nongthombam G. Singh, S. Tumtin, R. Nongrum and R. Nongkhlaw; One-pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones catalyzed by cupric acetate under solvent-free conditions. J. Chin. Chem. Soc., 2014, 61, 1254-1258.
  • N. G. Singh, R. Nongrum, C. Kathing, J. W. S. Rani and R. Nongkhlaw; Bakers' yeast: An environment benign catalyst for the one-pot synthesis of Indolyl chromenes and Bisindolylalkanes. Green Chem. Lett. & Rev., 2014, 7, 137-144.
  • N. G. Singh, C. Kathing, J. W. S. Rani and R. Nongkhlaw; An efficient and versatile protocol for the synthesis of bis(indolyl)alkanes and tris(indolyl)alkanes using chlorotrimethylsilane. J. Chin. Chem. Soc., 2014, 61, 442-446.
  • C.Kathing, S.Tumtin, N.G.Singh, J.W.Rani, I.T.Phucho, A.Nongpiur, R.Nongrum and R.L.Nongkhlaw; Cupric acetate catalysed alkylation of indoles in water: A comparative study between conventional heating and microwave irradiation. Organic Chemistry An Indian Journal, 2013, 9, 257- 266.
  • A. S. Devi, P. Helissey, R. Nongkhlaw and J. N. Vishwakarma; KHSO4 –assisted Michael addition-Elimination reactions of Indoles dimethyl amino-1-phenylprop-2-en-1-ones in water: An Environment friendly synthesis of Novel 3-indolylchalcone. Synth.Commun., 2013, 43, 1653- 1660.
  • B. M Laloo, H. Mecadon, Md. R. Rohman, I. Kharbangar, I. Kharkongor, M. Rajbangshi, R, Nongkhlaw and B. Myrboh. Reaction of Selenium Dioxide with Aromatic Ketones in the Presence of Boron triflouride Etherate: A protocol for the Synthesis of Triarylethanones. J. Org. Chem., 2012, 77, 707- 712.
  • I. T. Phucho, S. Tumtin, A. Nongpiur, R. Nongrum, C. Kathing and R. Nongkhlaw. Microwave assisted synthesis of 3-substituted-4(3H)-quinazolinone using silica supported potassium carbonate. Organic Chemistry an Indian Journal; 2012, 8, 145 – 150.
  • M. Saha, E. Karim, J. N. Vishwakarma and R. Nongkhlaw. Microwave Assisted One-pot Synthesis of Novel bioactive 1-Phenylethylhexahydroquinazolin-5(6H)-ones & bis-1-Phenylethylhexahydroquinazolin-5(6H)-ones. Chemical Sciences Journal, 2012, 89, 117- 120.
  • S. Tumtin, T. Phucho, A. Nongpiur, R. Nongrum and R. Nongkhlaw; One pot synthesis of [1,3]-oxazine and [1,3]-thiazine derivatives under thermal and microwave conditions. Journal of Heterocyclic Chemistry, 2010, 47, 125-130.
  • I. T. Phucho, S. Tumtin, A. Nongpiur, R. Nongrum and R. Nongkhlaw; Microwave assisted synthesis of 6-?methyl-?1,?2,?3,?4-?tetrahydro-?N-?aryl-?2-?oxo-?4-?arylpyrimidine-?5-?carboxamide and 3,?4-?dihydropyrimidin-?2(1H)?-?ones under solvent free conditions. Journal of Chemical and Pharmaceutical Research2010, 2(3), 214-222.
  • A. S. Devi, M. C. Dutta, R. Nongkhlaw and J. N. Vishwakarma. KHSO4 assisted Michael addition-?elimination reactions of formylated acetophenones in water: a facile general green synthetic route to 3-?(alkyl?/aralkyl?/aryl) ?amino-?1-?arylprop-?2-?en-?1-?ones. Journal of the Indian Chemical Society2010, 87(6), 739-742.  
  • M. C. Dutta, K. Chanda, R. Nongkhlaw and J. N. Vishwakarma, A facile microwave-?assisted one-?pot strategy for the synthesis of bis-?hexahydroquinazolin-?5(6H)?-?ones. E-Journal of Chemistry, 2010, 7(1), 281-286.
  • J. N. Vishwakarma, M. C. Dutta, K. Chanda, B. Das, M. A. Laskar, and R. Nongkhlaw, Synthesis and anti-?bacterial activities of novel 5-?isonicotinoyl-?1,?2,?3,?4-?tetrahydropyrimidines and bis(5-?isonicotinoyl-?1,?2,?3,?4-?tetrahydropyrimidines). ARKIVOC (Gainesville, FL, United States) 2009, (13), 131-141.
  • I. T. Phucho,.; A. Nongpiur,.; S. Tumtin,.; R. Nongrum,.; R. Nongkhlaw; Recent progress in the chemistry of dihydropyrimidinones; Rasayan Journal of Chemistry (2009), 2(3), 662-676. 
  • I. T Phucho, S. Tumtin, A. Nongpiur, R. Nongrum, C. Kathing, R. Nongkhlaw; Microwave assisted synthesis of 6-?methyl-?1,?2,?3,?4-?tetrahydro-?N-?aryl-?2-?oxo-?4-?arylpyrimidine-?5-?carboxamide and 3,?4-?dihydropyrimidin-?2(1H)?-?ones under solvent free conditions; Journal of Chemical and Pharmaceutical Research, 2010, 2(3), 214-222
  • I. T Phucho, S. Tumtin, A. Nongpiur, R. Nongrum, C. Kathing, R. Nongkhlaw; Synthesis of 3,?4-?dihydro-?2(1H)?-?pyrimidinone and 3,?4,?5,?6,?7,?8-?hexahydro-?2(1H)?-?quinazolinones via three component  cyclocondensation; Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2010,  49B(3), 346-350
  • I. T Phucho, A. Nongpiur, S. Tumtin, R. Nongrum, B. Myrboh and R. Nongkhlaw, Novel one pot synthesis of substituted 1,?2,?4-?triazines. ARKIVOC (Gainesville, FL, United States) 2008, (15), 79-87.
  • R. Nongkhlaw and B Myrboh, Novel one-?pot synthesis of substituted 1,?2,?4-?triazines. Heterocyclic Communications, 2006, 12(1), 67-72.  
  • R. Nongkhlaw, R. Nongrum, I. Nongkynrih, F. Mathew and B. Myrboh, Novel synthesis of substituted cyclopropane acetic acid ethyl esters from cyclopropyl alkyl ketones. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2005, 44B (5), 1054-1057.
  • R. Nongkhlaw, R. Nongrum, and B. Myrboh, A novel one-?pot synthesis of substituted pyridazines: A general method of preparation of 3,?4,?6-?triarylpyridazines, Heterocyclic Communications2003, 9(5), 465-472.
  • R. Nongkhlaw, R. Nongrum, and B. Myrboh, Synthesis of substituted hexa-3,5-dienoic acid methyl esters from conjugated dienones. Journal of the Chemical Society, Perkin Transactions 1, 2001, (11), 1300-1303.  

Collaboration/Consultancy:

  • Research Collaborations with the Department of Zoology and Department of Biotechnology, NEHU.

Any other

  • Resource Person in Lectures, Talks, Refresher Course, Orientation Programmes, workshops etc.
  • Chairperson of sessions in Conferences and Seminars.
  • Co-ordinator of SALTER’s- Royal Society of Chemistry (London) Science Camp, Dr. Yusuf Hamied- RSC Inspirational Chemistry Programme including teachers training Program.
  • Co-ordinator of RBPT’s workshop and training program conducted by COSME, IISER, Pune.

Reviewers for journals of national/international repute:

  1. Tetrahedron (Elsevier),
  2. Chemistry Select (Wiley)
  3. Journal of Inorganic and Organometallic Polymers and Materials (Springer)
  4. Dyes and Pigments(Elsevier)
  5. Polycyclic Aromatic Compounds,
  6. Tetrahedron Letters